منابع مشابه
Multidrug resistance during chemical carcinogenesis: a mechanism revealed?
The classic Solt-Farber model of chemical carcinogenesis in rat liver (7) involves sequential treatment of rats with diethylnitrosamine, partial hepatectomy, and 2(acetylamino)fluorene (AAF). After several weeks, the rats develop multiple preneoplastic hepatic nodules, and some of these become frank hepatocarcinomas after several months. Cells derived from the nodules appear to be resistant to ...
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ژورنال
عنوان ژورنال: Nature Reviews Clinical Oncology
سال: 2011
ISSN: 1759-4774,1759-4782
DOI: 10.1038/nrclinonc.2011.195